Staying Active May Slow Key Alzheimer’s Marker, Study Finds
A new study suggests that regular exercise may slow down the rise of a key Alzheimer’s-related protein in the blood—but only up to a certain point.
Researchers analyzed over 550 older adults (aged 70+) with memory complaints. They tracked their physical activity levels and measured a protein called phosphorylated tau181 (p-tau181), which is linked to Alzheimer’s disease.
• People who exercised more had a slower increase in p-tau181 levels over time compared to those who were inactive.
• Both low and high levels of moderate to vigorous exercise were linked to this benefit.
• However, for people who already had high levels of p-tau181, exercise did not seem to improve cognitive function.
Why This Matters
This study reinforces the idea that staying active is a powerful tool for brain health. While exercise alone may not be a cure for Alzheimer’s, it could help slow down brain changes linked to the disease—especially if started early.
What You Can Do
• Aim for at least 150 minutes of moderate to vigorous exercise per week (like brisk walking, cycling, or dancing).
• Don’t wait—the earlier you build an active lifestyle, the better it may protect your brain.
• Combine exercise with other brain-healthy habits, such as a balanced diet, social engagement, and good sleep.
The Bottom Line
Staying active isn’t just good for your body—it could help protect your brain, too. Even small lifestyle changes can make a big difference over time!