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Probiotics: Science or Hype?

What Are Probiotics?

Probiotics are live microorganisms (bacteria or yeast) that, when taken in adequate amounts, support health—primarily by improving gut function and immunity.


Health Benefits

  • Immunological Effects: Enhance immune responses, stimulate antibody production, and reduce food antigen sensitivity.
  • Non-immunological Effects: Aid digestion, block harmful bacteria, produce protective substances, strengthen the intestinal lining, and neutralize toxins.

How They Work

  • Antimicrobial Action: Inhibit harmful bacteria through pH control and antimicrobial substances.
  • Gut Barrier Protection: Strengthen mucosal integrity and stimulate mucus production.
  • Immune Modulation: Influence immune cells and reduce inflammation.

Regulation & Usage

  • Considered nutritional supplements in the US/EU.
  • Must follow FAO/WHO guidelines on labeling, safety, and efficacy.
  • Common strains include LactobacillusBifidobacterium, and Saccharomyces cerevisiae.

Key Characteristics

  • Safety: Widely recognized as safe.
  • Viability: Must survive the digestive tract to be effective.
  • Efficacy: Requires clinically proven strain-specific benefits.
  • Stability: Must remain active through shelf life.
  • Labeling: Must include strain details, dosage, storage, and benefits.


Safety Profile

Probiotics have a very low risk of side effects. For example, only 1 adverse case per 10 million users of Lactobacillusstrains has been reported.

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